Electrospinning is a process used to fabricate continuous nanoscale fibers with diameters in the sub-micrometer to nanometer range using a high-voltage power supply.
What is electrospinning technology?
Electrospinning (ES) is a technology to obtain nanomaterials formed by the deposition of polymer nanofibers, which results in an interconnected three-dimensional network [6]. Despite their extremely small diameter, these nanofibers show large surface area to volume ratio and high porosity.
Which nanofiber can be used in case of drug delivery?
PCL nanofibers released nearly 100% of the incorporated IBU in 4 h, demonstrating the influence of drug properties, such as molecular weight and solubility on the release from the polymer matrix [11]. Vrbata et al. (2013), incorporated NP in fibers.
What is the driving force for electrospinning?
Electrospinning is a fiber production method which uses electric force to draw charged threads of polymer solutions or polymer melts up to fiber diameters in the order of some hundred nanometers. Electrospinning shares characteristics of both electrospraying and conventional solution dry spinning of fibers.
When was electrospinning developed?
John Francis Cooley filed the first electrospinning patent in 1900. In 1914 John Zeleny published work on the behaviour of fluid droplets at the end of metal capillaries. His effort began the attempt to mathematically model the behavior of fluids under electrostatic forces.
Why polymers are used in electrospinning?
Natural polymers are preferred over synthetic polymers in medical and biological uses because of their low immunogenicity and better biocompatibility. Recent researchers have reported the use of electrospinning process of natural polymers such as gelatine, collagen, and silk fibroin [36–41].
What are the properties of nanofibers?
Nanofibers are long polymeric filaments, which exhibits the ideal advantages in high porosity, high surface area, high encapsulation efficiency, and controllable morphology, high chemical and thermal stability. The properties of nanofibres could significantly influence the polymeric raw material.
Which of the following techniques are used for the preparation of nanofibers?
The process widely used for the fabrication of nanofibres is electrospinning,6–7 because of its simplicity and suitability for a variety of polymers, ceramics and metals. Other processes include meltblowing, flash-spinning, bicomponent spinning, forcespinning, phase-separation and drawing.
